5-deaza-10-oxo- and 5-deaza-10-thio-5, 6, 7,...

Details 5-deaza-10-oxo- and 5-deaza-10-thio-5, 6, 7,... 5-deaza-10-oxo- and 5-deaza-10-thio-5, 6, 7,...

C - Chemistry, Metallurgy

07

D

C07D 475/04 (2006.01) A61K 31/505 (2006.01) A61K 31/695 (2006.01) C07C 235/52 (2006.01) C07D 211/76 (2006.01) C07D 471/04 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2085299

Abstract 5-Deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8- tetrahydrofolic acid derivatives are provided as agents useful for treating susceptible neoplasms in mammals. Pharmaceutical formulations and intermediates are also provided.

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