5-(dihydroxphenoxy) tetrazoles as sweeteners

C - Chemistry – Metallurgy – 07 – D

Patent

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260/312, 99/140.

C07D 257/04 (2006.01) A23L 1/226 (2006.01) A23L 1/236 (2006.01)

Patent

CA 1153003

Abstract of the Disclosure 5-(Dihydroxyphenoxy)-1H-tetrazoles and their nontoxic, physiologically acceptable salts are used as non-nutritive sweeteners. These novel compounds are prepared by demethylation of the corresponding 5-(dimethoxyphenoxy)-1H-tetrazoles. The 5-(dihydroxyphenoxy)- 1H-tetrazoles of this invention have the following formula: Image wherein each R is hydroxy. The preferred compound is 5-(2,3-dihydroxyphenoxy)-1H-tetrazole.

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