5' ests and encoded human proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/10 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G06F 17/30 (2006.01) G06F 17/50 (2006.01)

Patent

CA 2319089

The sequences of 5' ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5' ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5' ESTs. The 5' ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be otained using the 5' ESTs. The 5' ESTs may also be used to design expression vectors and secretion vectors.

L'invention concerne des EST des séquences 5' dérivées à partir d'acides ARNm codant pour les protéines sécrétées. Les EST des 5' peuvent servir pour obtenir des ADNc et des ADN génomiques qui correspondent aux EST des 5'. On peut aussi utiliser les EST des 5' dans des opérations de diagnostic, de médecine légale, de thérapie génique et de mappage des chromosomes. En utilisant des EST des 5', on peut aussi obtenir des séquences de régulation en aval ou concevoir des vecteurs d'expression et des vecteurs de sécrétion.

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