5'ests for non tissue specific secreted proteins

Details 5'ests for non tissue specific secreted proteins 5'ests for non tissue specific secreted proteins

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2297306

The sequences of 5'ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5'ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5'ESTs. The 5'ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be obtained using the 5'ESTs. The 5'ESTs may also be used to design expression vectors and secretion vectors.

Cette invention présente les séquences de marqueurs séquentiels exprimés 5' (EST 5') dérivés d'ARNm codant des protéines sécrétées. Ces EST 5' peuvent servir à obtenir des ADNc et des ADN génomiques correspondant aux EST 5'. Ces EST 5' peuvent également servir dans les diagnostics, en médecine légale, dans les thérapies géniques et dans les procédures de mappage de chromosomes. On peut également obtenir des séquences régulatrices en amont en utilisant ces EST 5', lesquels peuvent également servir pour la mise au point de vecteurs d'expression et de vecteurs de sécrétion.

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