5' ests for secreted proteins expressed in testis and other...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/10 (2006.01) C12N 15/66 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2297157

The sequences of 5' ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5' ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5' ESTs. The 5' ESTs may also be used in diganostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be obtained using the 5' ESTs. The 5' ESTs may also be used to design expression vectors and secretion vectors.

L'invention concerne des séquences d'EST 5' (marqueurs séquentiels exprimés) dérivés d'ARNm codant des protéines sécrétées. Les EST 5' peuvent être utilisés pour la production d'ADNc et d'ADN génomiques correspondant aux EST 5'. Les EST 5' peuvent également être utilisés dans le diagnostic, la médecine légale, la thérapie génique et les procédures de cartographie des gènes. Des séquences de régulation d'amont peuvent également être produites au moyen des EST 5'. Les EST 5' peuvent également être utilisés pour la mise au point de vecteurs d'expression et de vecteurs de sécrétion.

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