5-fluorobenzonitrile derivatives and pharmacologically...

Details 5-fluorobenzonitrile derivatives and pharmacologically... 5-fluorobenzonitrile derivatives and pharmacologically...

A - Human Necessities

23

K

99/24.1, 260/558

A23K 1/16 (2006.01)

Patent

CA 1260954

5-FLUOROBENZONITRILE DERIVATIVES AND PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREFOR FOR INCREASING THE LEAN MEAT TO FAT RATIO, AND/OR ENHANCING THE GROWTH RATE OF WARM-BLOODED ANIMALS ABSTRACT There are provided novel 5-fluorobenzonitrile derivatives having the following general formula: Image wherein R is isopropyl or tert-butyl; and the optical isomers thereof and the non-toxic, pharmacologically acceptable acid addition salts thereof. These compounds exhibit low .beta.1 heart stimulant activity and are useful for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals by, orally or parenterally, administering to said animals an amount of a 5-fluorobenzonitrile derivative or a pharmacologically acceptable salt thereof effective for achieving one or more of the above-identified metabolic improvements in said warm-blooded animals.

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