5-halo-tryptamine derivatives used as ligands of the 5-ht6...

Details 5-halo-tryptamine derivatives used as ligands of the 5-ht6... 5-halo-tryptamine derivatives used as ligands of the 5-ht6...

C - Chemistry, Metallurgy

07

D

C07D 209/16 (2006.01) A61K 31/4045 (2006.01) A61P 1/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2455296

Compounds of Formula (I): (I); wherein: R1 and R2 either the same or different, are H or linear or branched C1-C6 alkyl; R3 = linear or branched C1- C6 alkyl; R4 = halogen, and pharmaceutically acceptable salts thereof are useful as active ingredients in the preparation of medicaments used as ligands of the 5-HT6 and/or 5-HT7 serotoninergic receptors.

L'invention concerne des composés de formule (I), dans laquelle R¿1 ?et R¿2? sont soit identiques soit différents, représentent H ou alkyle en C¿1?-C¿6? linéaire ou ramifié ; R¿3? = alkyle en C¿1?-C¿6? linéaire ou ramifié et R¿4? = halogène. Cette invention concerne également des sels pharmaceutiquement acceptables desdits composés, utilisés comme ingrédients actifs dans la préparation de médicaments utilisés comme ligands des récepteurs sérotoninergiques 5-HT¿6? et/ou 5-HT¿7?.

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