5-ht1a and 5-ht1d.alpha. antagonists

A - Human Necessities – 61 – K

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A61K 31/445 (2006.01) C07D 491/113 (2006.01) C07D 491/20 (2006.01)

Patent

CA 2291674

A class of novel substituted-aryloxy-2-ol-3-(4-spiro- (alkanedioxy)isobenzofuranyl- and phthaloyl-piperidine) derivatives is disclosed useful as 5-HT1A and 5-HT1D.alpha. antagonists.

Cette invention se rapporte à une classe de nouveaux dérivés aryloxy-2-ol-3-(4-spiro-(alcanedioxy)isobenzofuranyl- et phtaloyl-pipéridine) substitués qui s'avèrent utiles en tant qu'antagonistes de 5-HT¿1A? ET 5-HT¿1D.alpha.?.

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