C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/42 (2006.01) A61K 31/4365 (2006.01) A61K 31/4706 (2006.01) A61P 9/00 (2006.01) A61P 21/00 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2551552
The present invention provides certain compounds, pharmaceutical formulations thereof, and methods for the treatment of conditions mediated by 5-HT2 receptors. These compounds provide for modulation of the signals mediated by 5- HT2 receptors, specifically those receptors in the cardiovascular system. Thus, these compounds may be used alone or in conjunction with other drugs to treat cardiovascular diseases such as, but not limited to, muscle atrophy, cardiac hypertrophy, heart failure, and primary pulmonary hypertension.
La présente invention a trait à certains composés, leurs formulations pharmaceutiques, et des procédés pour le traitement de conditions liées aux récepteurs 5-HT2. Ces composés assurent la modulation des signaux transmis par l'intermédiaires des récepteurs 5-HT2, plus spécifiquement ces récepteurs se trouvant dans le système cardio-vasculaire. Ainsi, ces composés peuvent être utilisés seuls ou en combinaison avec d'autres médicaments pour le traitement de maladies cardio-vasculaires, telles que, mais de manière non exclusive, l'atrophie musculaire, l'hypertrophie cardiaque, et l'hypertension pulmonaire primaire.
Bush Erik
Melvin Larry
Bcf Llp
Myogen Inc.
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