5-ht4 receptor antagonists

Details 5-ht4 receptor antagonists 5-ht4 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/245 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/437 (2006.01) A61K 31/4427 (2006.01) A61K 31/443 (2006.01) A61K 31/445 (2006.01) A61K 31/4453 (2006.01) A61K 31/452 (2006.01) A61K 31/454 (2006.01) A61K 31/47 (2006.01) A61K 31/55 (2006.01) C07D 209/42 (2006.01) C07D 319/18 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 411/12 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 455

Patent

CA 2118812

The use of a compound of formula (I) or pharmaceutically acceptable salt thereof, in which X1-(CH2)x-X2 forms a 5-7 membered ring wherain:X1 is O or S; X2 is O; S, NR or NRCO wherein R is hydrogen or C1-6alkyl; x is 1, 2 or 3; Y is O or NH; Z is sub-formula (a); (b) or (c) in the manufacture of a medicament for use in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.

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