5-ht7 receptor antagonists

Details 5-ht7 receptor antagonists 5-ht7 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 217/04 (2006.01) A61K 31/47 (2006.01) A61K 31/4725 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2575785

The invention relates to compounds of formula (I) having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline propyl sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5- HT is involved, such as CNS disorders.

L'invention concerne des composés de formule (I) à activité pharmacologique vis-à-vis du récepteur 5-HT7, et plus précisément de certains composés tétrahydroisoquinoline propyl sulfonamide, des procédés d'élaboration de tels composés, des compositions pharmaceutiques qui les renferment, et leur utilisation pour le traitement et la prophylaxie d'une maladie faisant intervenir le 5-HT, du type trouble du système nerveux central.

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