5-ht7 receptor antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/00 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) C07D 239/02 (2006.01) C07D 239/48 (2006.01) C07D 239/50 (2006.01) C07D 251/02 (2006.01) C07D 251/54 (2006.01) C07D 251/70 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01)

Patent

CA 2409729

Amino-pyrimidine and amino-triazine derivatives having 5-HT7 antagonist activity for the treatment of sleeping disorders, depression, schizophrenia, anxiety, obsessive compulsive disorders, circadian rhythm disorders, ocular disorders and/or centrally and peripherally mediated hypertension are provided.

L'invention concerne des dérivés d'amino-pyrimidine et d'amino-triazine présentant une activité antagoniste de 5-HT¿7? utile pour traiter les troubles du sommeil, la dépression, la schizophrénie, l'anxiété, les troubles obsessionnels compulsifs, les troubles du rythme nycthéméral, les troubles oculaires et/ou l'hypertension d'origine centrale et périphérique.

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