5-lipoxygenase activating protein

C - Chemistry – Metallurgy – 12 – N

Patent

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167/129, 530/13,

C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07D 209/30 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2032253

An 18kD protein (FLAP) has been isolated from rat and human cells which is necessary for production of leukotrienes from arachidonic acid in mammalian cells containing 5-lipoxygenase. The gene (cDNA) encoding for FLAP has also been produced.

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