5-lipoxygenase-activating protein (flap) inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/12 (2006.01) A61K 31/404 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/4709 (2006.01) A61K 31/501 (2006.01) A61K 31/5377 (2006.01) C07D 209/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2628233

Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.

L'invention concerne des composés et des compositions pharmaceutiques contenant de tels composés qui modulent l'activité de la protéine d'activation de la 5-lipoxygénase (FLAP). Cette invention a aussi pour objet des méthodes d'utilisation de tels modulateurs de la protéine d'activation de la 5-lipoxygénase (FLAP), seuls ou combinés avec d'autres composés, dans le traitement de troubles ou de maladies respiratoires, cardio-vasculaires et autres dépendants du leukotriène ou médiés par le leukotriène.

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