C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/404 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/4709 (2006.01) A61K 31/501 (2006.01) A61K 31/5377 (2006.01) C07D 209/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2628233
Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
L'invention concerne des composés et des compositions pharmaceutiques contenant de tels composés qui modulent l'activité de la protéine d'activation de la 5-lipoxygénase (FLAP). Cette invention a aussi pour objet des méthodes d'utilisation de tels modulateurs de la protéine d'activation de la 5-lipoxygénase (FLAP), seuls ou combinés avec d'autres composés, dans le traitement de troubles ou de maladies respiratoires, cardio-vasculaires et autres dépendants du leukotriène ou médiés par le leukotriène.
Evans Jillian F.
Haddach Mustapha
Hutchinson John H.
Li Yiwei
Moran Mark
Amira Pharmaceuticals Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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