C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/00 (2006.01) A61K 31/415 (2006.01)
Patent
CA 2628490
Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
L'invention concerne des composés et des compositions pharmaceutiques contenant de tels composés qui modulent l'activité de la protéine d'activation de la 5-lipoxygénase (FLAP). Cette invention a aussi pour objet des méthodes d'utilisation de modulateurs de la protéine d'activation de la 5-lipoxygénase (FLAP), seuls et combinés à d'autres composés dans le traitement de troubles ou de maladies respiratoires, cardio-vasculaires et dépendants de la leukotriène ou médiés par la leukotriène.
Arruda Jeannie M.
Evans Jillian F.
Haddach Mustapha
Hutchinson John H.
Li Yiwei
Amira Pharmaceuticals Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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