5-membered annelated heterocyclic pyrimidines as kinase...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/32 (2006.01) A61K 31/519 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2594425

This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, Q1, Q2, X1, X2, Y and Z have defined meanings, having cell cycle kinase inhibiting enzymatic activity, their preparation, compositions containing them and their use as a medicine.

L'invention concerne de nouveaux composés correspondant à la formule (I) dans laquelle R1, R2, R3, R4, R5, R6, Q1, Q2, X1, X2, Y et Z ont des valeurs déterminées, qui ont une activité enzymatique d'inhibition de kinases, leur préparation, les compositions les comprenant et leur utilisation en tant que médicaments.

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