5-methanesulfonamido-3h-isobenzofuran-1-ones as inhibitors...

C - Chemistry – Metallurgy – 07 – D

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C07D 405/12 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2211320

The invention encompasses the novel compound of formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of formula (I).

L'invention se rapporte aux nouveaux composés de la formule (I) ainsi qu'à un procédé de traitement des maladies induites par la cyclooxygénase-2, ce procédé consistant à administrer à un patient nécessitant ce type de traitement une quantité non toxique, thérapeutiquement efficace, d'un composé de la formule (I). L'invention se rapporte également à certaines compositions pharmaceutiques utilisées dans le traitement des maladies induites par la cyclooxygénase-2 comprenant les composés de la formule (I).

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