5-oxo-5h-¬1|benzopyrano¬2,3-b|pyridine derivatives, their...

Details 5-oxo-5h-¬1|benzopyrano¬2,3-b|pyridine derivatives, their... 5-oxo-5h-¬1|benzopyrano¬2,3-b|pyridine derivatives, their...

C - Chemistry, Metallurgy

07

D

260/276.2

C07D 491/052 (2006.01) C07D 491/04 (2006.01)

Patent

CA 1200243

Abstract The present invention relates to novel 5-oxo-5H- ?1?benzopyrano(2,3-b)pyridine derivatives useful for effective medicines for the treatment of various connective tissue diseases such as chronic rheumatoid arthritis and varieties of inflammatory diseases caused by immunoreaction, which are shown by the following formula: Image wherein R is the same or different and represents hydrogen, alkyl, alkoxy, nitro, hydroxyl, acyl, hydroxyalkyl, halogen with the proviso that m is 1,2 or 3, or a tetramethylene (-(CH2)4-) or butadienylene (-CH=CH-CH=CH-) group which, in conjunction with two adjacent carbon atoms on the ring, forms a six-membered ring with the proviso that m is 1; n is 1 or 2, or a physiologically acceptable salt or ester thereof.

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