C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/435 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 221/16 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 491/04 (2006.01)
Patent
CA 2488929
This invention provides novel arylindenopyridines of formula: (I), and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing Adensine A2a receptors or reducing PDE activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.
L'invention concerne de nouvelles arylinedénopyridines de formule (I) et des compositions pharmaceutiques renfermant celles-ci, utilisées pour le traitement de maladies, amélioré par antagonisation de récepteurs d'adénosine A2a ou réduction de l'activité PDE dans des cellules appropriées. L'invention concerne également des méthodes thérapeutiques et prophylactiques au moyen des présentes compositions pharmaceutiques.
Averill Kristin M.
Demarest Keith T.
Dodd John H.
Heintzelman Geoffrey R.
Jackson Paul F.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Ortho-Mcneil Pharmaceutical Inc.
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