A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/37 (2006.01) A61K 31/366 (2006.01) C07D 493/02 (2006.01)
Patent
CA 2581859
Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects, including autoimmune diseases. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition. In some embodiments, the compounds are more selective for certain potassium channels (e.g., Kv1.3 channels) than other potassium channels (e.g., Kv1.5 channels).
L'invention concerne des compositions comprenant des composés du 5-phénoxyalkoxypsoralène et leur procédé de synthèse et d'utilisation. Les composés peuvent être utilisés pour traiter des maladies ou des troubles chez des humains ou des animaux, notamment les maladies auto-immunes. Les composés inhibent les canaux potassiques, notamment le canal Kv1.3 et au moins certains des effets thérapeutiques des composés peuvent être provoqués au moins en partie par l'inhibition du canal potassique. Dans certains modes de réalisation, les composés sont plus sélectionnés pour certains canaux potassiques (par exemple les canaux Kv1.3) que pour les autres canaux potassiques (par exemple les canaux Kv1.5).
Haensel Wolfram
Sankaranarayanan Ananthakrishnan
Schmidt-Lassen Kristina
Schmitz Alexander
Wulff Heike
Gowling Lafleur Henderson Llp
The Regents Of The University Of California
LandOfFree
5-phenoxyalkoxypsoralens and methods for selective... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 5-phenoxyalkoxypsoralens and methods for selective..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-phenoxyalkoxypsoralens and methods for selective... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2008529