5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as...

Details 5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as... 5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 277/48 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/5377 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2533175

Compounds of Formula (I) in free or salt form, wherein Ra, Rb, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3- kinase such as inflammatory airway diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

Composés de formule (I), sous forme libre ou de sel, dans laquelle R?a¿, R?b¿, R?2¿, R?3¿, R?4¿ et R?5¿ possèdent la signification figurant dans le descriptif, qui sont utiles pour traiter des états médiés par la phosphatidylinositol 3-kinase. Des compositions pharmaceutiques qui contiennent ces composés et un procédé de préparation desdits composés sont également décrits.

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