5-phenylthiazole derivatives and their use as p13 kinase...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/427 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2517708

Compounds of formula (I) in free or salt form, wherein R1, R2, R3, Wand R5 have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Composés représentés par la formule (I) sous forme libre ou sous forme de sel, dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ possèdent les significations indiquées dans les revendications. Ces composés sont utiles pour traiter des maladies dans lesquelles phosphatidylinositol 3-kinase joue un rôle. Compositions pharmaceutiques contenant ces composés et méthodes servant à préparer ces composés.

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