5-substituted 2,3-dihydrobenzofuran-2-carboxylic acids and...

Details 5-substituted 2,3-dihydrobenzofuran-2-carboxylic acids and... 5-substituted 2,3-dihydrobenzofuran-2-carboxylic acids and...

C - Chemistry, Metallurgy

07

D

260/364, 260/361

C07D 307/78 (2006.01) C07D 307/80 (2006.01) C07D 307/85 (2006.01)

Patent

CA 1190237

Abstract of the Disclosure Described are compounds of the formula Image wherein R1 and R2 independently of one another denote hydrogen or loweralkyl; A is CO, CH2, O, S, SO or CHOH; X is hydrogen, halo, loweralkyl, or -CH2NR1R2 wherein R1 and R2 are as defined above; W is COOR wherein R is hydrogen or alkyl of 1-10 carbon atoms, CH2OH, CONR1R2 or CH2NR1R2 wherein R1 and R2 are as defined above; Z1 and Z2 independently of one another denote hydrogen, halo or loweralkyl; and pharmaceutically acceptable salts thereof. The compounds are effective as diuretic agents.

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