5-substituted 2-pyrimidinone nucleosides and methods of use

Details 5-substituted 2-pyrimidinone nucleosides and methods of use 5-substituted 2-pyrimidinone nucleosides and methods of use

C - Chemistry, Metallurgy

07

H

260/229.2

C07H 19/06 (2006.01) C07D 239/34 (2006.01) C07D 239/36 (2006.01) C07H 19/16 (2006.01)

Patent

CA 1259611

ABSTRACT OF THE DISCLOSURE Compounds for inhibiting the replication of DNA viruses which induce the formation of thymidine kinase enzyme. These compounds have the formula: Image wherein R1 is a radical selected from the group consisting of chloro, iodo, hydroxy, alkoxyalkyl, hydroxyalkyl, methylamino, formyl, nitro, and unsubstituted hydrocarbon groups of 2 to about 3 carbon atoms or halosubstituted hydrocarbon groups of 1 to about 3 carbon atoms; R2 is hydrogen or hydroxy; and R3 is hydroxy, -OP(O) (OH)2, amino, or -OCOR4 where R4 is alkyl or alkoxyalkyl of 2 to about 18 carbon atoms.

461607

Affiliated with

Also associated with

Rating

5-substituted 2-pyrimidinone nucleosides and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-substituted 2-pyrimidinone nucleosides and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-substituted 2-pyrimidinone nucleosides and methods of use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1319319