5-(substituted)aryloxazolidin-4-one-2-thiones

Details 5-(substituted)aryloxazolidin-4-one-2-thiones 5-(substituted)aryloxazolidin-4-one-2-thiones

C - Chemistry, Metallurgy

07

D

260/311.7

C07D 263/46 (2006.01)

Patent

CA 1164873

ABSTRACT Disclosed herein are 5-(substituted)aryloxazolidin-4-one-2- thione of the formula Image wherein R6 is Image or Image in which W is fluoro; W1 is benzyloxy, chloro, phenoxy, nitro or trifluoromethyl; W2 is benzyloxy, phenoxy, nitro or trifluoromethyl; W3 is methyl, (C1-C2)alkoxy, methylthio, chloro or fluoro; W4 and W5 are each independently hydrogen, methyl, bromo, chloro, fluoro, cyano, nitro or trifluoromethyl; Y is hydrogen, methyl, benzyloxy, (C1-C2)alkoxy, chloro, bromo or fluoro; y1 is hydrogen or methoxy; and y2 is fluoro or chloro. The oxazolidin-4-one-2-thiones are useful as intermediate for preparing corresponding oxazolidine-2,4-diones having utility as hypoglycemic agents.

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