C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/242
C07D 471/04 (2006.01) A61K 31/395 (2006.01)
Patent
CA 1288430
5-SUBSTITUTED OCTAHYDROINDOLIZINE ANALGESICS COMPOUNDS AND 7-KETO INTERMEDIATES ABSTRACT Octahydroindolizidines and corresponding ketones of the formulae (I) and (II): (I) Image Image (II) where A is a 3-7 carbon or hetero-containing ring, R1 is a substituent, n is 0-6 and x is 0-3. Also, pharmaceutical compositions for treating pain containing (I) or (II) and methods for synthesis and use as well as novel intermediates in the synthesis.
528770
Carmosin Richard J.
Carson John R.
Carmosin Richard J.
Carson John R.
Mcneilab Inc.
Swabey Ogilvy Renault
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