5-substituted thiazol-2-yl amino compounds and compositions...

Details 5-substituted thiazol-2-yl amino compounds and compositions... 5-substituted thiazol-2-yl amino compounds and compositions...

C - Chemistry, Metallurgy

07

D

C07D 277/42 (2006.01) A61K 31/427 (2006.01) C07D 277/46 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2615890

The invention provides 5-substituted thiazol-2-yl amino compounds of Formula (I): pharmaceutical compositions comprising such compounds and the use of such compounds for the treatment or prevention of diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of Ab 1 , Aurora-A, Ber-Ab1 , Bmx, CDKI/cyclinB, CHK2, Fes, FGFR3, Flt3, GSK3.beta., JNK1.alpha.1 , Lck, MKK4 and TrkB kinases.

La présente invention concerne une nouvelle classe de composés, des compositions pharmaceutiques comprenant de tels composés ainsi que des procédés d~utilisation de tels composés pour traiter les maladies ou les troubles associés à une activité kinase anormale ou dérégulée, en particulier les maladies ou les troubles impliquant une activation anormale des kinases Abl, Aurora-A, Bcr-Abl, Bmx, CDK1/cyclineB, CHK2, Fes, FGFR3, Flt3, GSK3.beta., JNK1.alpha.1, Lck, MKK4 et TrkB.

Affiliated with

Also associated with

Rating

5-substituted thiazol-2-yl amino compounds and compositions... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-substituted thiazol-2-yl amino compounds and compositions..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-substituted thiazol-2-yl amino compounds and compositions... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1372115