5-(w-phenethylamino-alkyl)-4,5,6,7-tetrahydro-thieno-...

Details 5-(w-phenethylamino-alkyl)-4,5,6,7-tetrahydro-thieno-... 5-(w-phenethylamino-alkyl)-4,5,6,7-tetrahydro-thieno-...

C - Chemistry, Metallurgy

07

D

167/231, 260/276

C07D 495/04 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1292233

A B S T R A C T This invention relates to new derivatives of 5(.omega.-phenethylamino-alkyl)-4,5,6,7-tetrahydro-thieno-(3,2-c)- pyridine of the formula Image wherein n is an integer of from 2 to 5, R1 represents a hydrogen atom or a 3,4-dimethoxyphenyl group, R2 represents a hydrogen atom, an alkyl group having up to 4 carbon atoms or a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group and R3 represents two or three methoxy groups, to therapeutically acceptable salts thereof, to a process for the preparation of these derivatives comprising condensing a 5-(.omega. -chloroalkyl)- 4,5,6,7- tetrahydro- thieno- (3,2-c)- pyridine with the appropriate phenethyl derivative at from 90 to 130°C under nitrogen circulation and to therapeutic compositions containing said compounds.

495037

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