5h-(1)benzopyrano(3,4-d)pyridines

C - Chemistry – Metallurgy – 07 – D

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260/276.2

C07D 491/04 (2006.01) C07C 37/055 (2006.01) C07C 39/367 (2006.01)

Patent

CA 1037955

5H-[1]BENZOPYRANO[3,4-d]PYRIDINES Abstract of the Disclosure 5H-[1]Benzopyrano[3,4-d]pyridines represented by the formula Image wherein each R1 is loweralkyl, R2 is alkyl, cycloalkyl or Image wherein Y is a straight or branched chain alkylene group having from 1 to 10 carbon atoms and each R4, R5 and R6 are the same or different members of the group consisting of hydrogen, halo, trifluoro- methyl or loweralkyl; and R3 is hydroxy, acyloxy, loweralkoxy, loweralkenyloxy, loweralkynyloxy or Image X is a straight or branched chain alkylene group having from one to eight carbon atoms, and wherein R7 and R8 are the same or different members of the group consisting of hydrogen or loweralkyl, or -1- Image wherein X is a straight or branched chain alkylene group having from one to eight carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, Z is CH2, O, S or NR10 with R10 being hydrogen or loweralkyl, with the limitation that when Z is O or S, the sum of a and b is 3 or 4; and when Z is NR10 , the sum of a and b is 3-5; R9 is hydrogen or loweralkyl, and the pharmaceutically acceptable salts thereof.

203794

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