5t4 antigen expression as a marker for stem cell...

Details 5t4 antigen expression as a marker for stem cell... 5t4 antigen expression as a marker for stem cell...

G - Physics

01

N

G01N 33/569 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2490163

The present invention relates to methods for detecting the differentiation status of stem cells comprising detecting the expression of 5T4 antigen in said stem cells. The present invention also relates to methods for separating populations of undifferentiated or differentiated mammalian stem cells from a mixture of differentiated and undifferentiated stem cells through detection of 5T4 expression.

La présente invention concerne des procédés pour détecter l'état de différenciation de cellules souches. Ce procédé consiste à détecter l'expression d'un antigène 5T4 dans ces cellules souches. La présente invention concerne également des procédés pour séparer des populations de cellules souches de mammifère différenciées et non différenciées dans un mélange de cellules souches différenciées et non différenciées par détection de l'expression de 5T4.

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