(5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)am...

Details (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)am... (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)am...

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A61K 31/133 (2006.01) A61K 31/498 (2006.01) A61P 7/06 (2006.01) C07C 215/10 (2006.01)

Patent

CA 2611480

Invented is the compound (5Z)-5-(6-quinoxalinylmethylidene)-2-[(2,6- dichlorophenyl)amino]-1,3-thiazol-4(5H)-one, and/or pharmaceutically acceptable salts, hydrates, solvates and pro-drugs thereof. Also invented are pharmaceutical compositions containing this compound, methods of preparing this compound and pharmaceutically acceptable salts, hydrates, solvates and pro-drugs thereof. Also invented are methods of using this compound as an inhibitor of hYAK3 proteins.

Est inventé le composé (5Z)-5-(6-quinoxalinylméthylidène)-2-[(2,6-dichlorophényl)amino]-1,3-thiazol-4(5H)-one, et/ou ses sels, hydrates, solvates et promédicaments pharmaceutiquement acceptables. L~invention concerne également des compositions pharmaceutiques contenant ce composé, des méthodes de préparation de ce composé ainsi que de ses sels, hydrates, solvates et promédicaments pharmaceutiquement acceptables. L~invention concerne également des procédés d~utilisation de ce composé en tant qu~inhibiteur de protéines hYAK3.

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