6-0-methylerythromycin a derivatives

Details 6-0-methylerythromycin a derivatives 6-0-methylerythromycin a derivatives

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) C07H 17/00 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2096969

This invention aims to provide novel erythromycin A derivatives having a strong antimicrobial activity against Gram-negative bacteria and having against Gram-positive bacteria also a much stronger effect than compounds so far known. This invention provides 6-O-methylerythromycin A derivatives represented by the following formula (see above formula) (wherein R1 and R2 each represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, and A represents a nitrogen atom or a N->O group) and their pharmaceutically acceptable salts.

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