6-11 bicyclic ketolide derivatives

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2483678

The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

L'invention concerne des composés représentés par la formule (I), ou des sels, des esters ou promédicaments pharmaceutiquement acceptables de ces composés, qui possèdent des propriétés antibactériennes ; des compositions pharmaceutiques contenant ces composés et destinées à être administrées à une sujet nécessitant un traitement antibiotique ; des méthodes de traitement d'une infection bactérienne chez un sujet, qui consiste à administrer à celui-ci une composition pharmaceutique contenant les composés de l'invention ; un procédé de fabrication desdits composés.

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