6,16-dimethyl corticoids, their preparation and use

Details 6,16-dimethyl corticoids, their preparation and use 6,16-dimethyl corticoids, their preparation and use

C - Chemistry, Metallurgy

07

J

167/196, 260/69,

C07J 5/00 (2006.01) A61K 31/57 (2006.01) C07J 7/00 (2006.01) C07J 21/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1312856

Abstract 6, 16-Dimethyl corticoids, their preparation and use 6,16-Dimethyl corticoids of the general formula Image (I), in which ----- represents a single bond or a double bond, X represents a hydrogen atom, a fluorine atom, a chlorine atom or a bromine atom, R1 represents a formyl group, an alkanoyl or alkoxyalkyl group containing from 2 to 8 carbon atoms, or a benzoyl group, and Y represents a chlorine atom, 2 hydroxy group, a formyl group, an alkanoyloxy group containing from 2 to 8 carbon atoms, or a benzoyloxy group, their preparation and use as medicaments are described. The compounds show anti-inflammatory and anti- allergic properties and can be made up into pharma- ceutical preparation form with suitable carriers.

432599

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