6-(2,2,2-trifluoroethylamino)-7-chloro-2,3,4,5-tetrahydro-1h...

Details 6-(2,2,2-trifluoroethylamino)-7-chloro-2,3,4,5-tetrahydro-1h... 6-(2,2,2-trifluoroethylamino)-7-chloro-2,3,4,5-tetrahydro-1h...

C - Chemistry, Metallurgy

07

D

C07D 223/16 (2006.01) A61K 31/55 (2006.01) A61P 3/04 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2532020

The present invention provides a 7-chloro-6-(2,2,2-trifluoroethylamino)- 2,3,4,5-tetrahydro-1H-benzo[d]azepine of formula (I): or a pharmaceutically acceptable salt thereof, and its use as a selective 5-HT2c agonist for the treatment of 5-HT2c associated disorders including obesity, obsessive/compulsive disorder, anxiety, and depression.

La présente invention concerne une 7-chloro-6-(2,2,2-trifluoroéthylamino)-2,3,4,5-tétrahydro-1H-benzo[d]azépine de formule (I), ou un sel pharmaceutiquement acceptable dudit composé, ainsi que son utilisation comme agoniste de 5-HT¿2C? pour le traitement de troubles associés à 5-HT¿2C?, tels que l'obésité, le trouble obsessif-compulsif, l'anxiété et la dépression.

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