6,7-dialkoxy-3,4-dihydroisoquinolin-8-ol, process for...

Details 6,7-dialkoxy-3,4-dihydroisoquinolin-8-ol, process for... 6,7-dialkoxy-3,4-dihydroisoquinolin-8-ol, process for...

C - Chemistry, Metallurgy

07

D

C07D 217/24 (2006.01) C07D 217/18 (2006.01) C07D 217/26 (2006.01) C07D 401/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 491/04 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2116294

-45- ABSTRACT OF THE DISCLOSURE This invention relates to novel 6, 7 - dialkoxy - 3, 4 - dihydroisoquinolin - 8 - ols, a process for preparing the 6, 7 - dialkoxy - 3, 4 - dihydroisoquinolin - 8 - ols reioselectively and in a high yield utilizing the Bischler - Napieralski reaction, a process for synthesizing 6, 7 - dialkoxy - 1, 2, 3, 4 - tetrahydroisoquinolin - 8 - ols via the compounds, and use of the 6, 7 - dialkoxy - 3, 4 - dihydroisoquinolin - 8 - ols for preparation of the 6, 7 - dialkoxy - 1, 2, 3, 4 - tetrahydroisoquinolin - 8 - ols. It is possible, according to this invention, to obtain the 6, 7 - dialkoxy - 1, 2, 3, 4 - tetrahydroisoquinolin - 8 - ols, which have hitherto been difficult to synthesize, via the 6, 7 - dialkoxy - 3, 4 - dihydroisoquinolin - 8 - ols in a high yield.

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