6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1h,5h-...

Details 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1h,5h-... 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1h,5h-...

C - Chemistry, Metallurgy

07

D

167/227, 260/271

C07D 455/06 (2006.01) A61K 31/47 (2006.01) C07D 215/18 (2006.01) C07D 215/48 (2006.01) C07D 455/04 (2006.01)

Patent

CA 1254568

Abstract of the Disclosure The compound 6,7-dihydro-5,8-dimethyl-9-fluoro-1- oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid is disclosed as a potent antimicrobial agent with a broad spectrum of activity. Esters, acyl chlorides, alkylaminoalkyl ester salts and pharmaceutically acceptable carboxylate salts of the acid are also disclosed. Methods of using these compounds, pharmaceutical compositions comprising these compounds and synthetic intermediates for preparing these compounds are described.

439826

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