6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinoline- acetamide...

Details 6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinoline- acetamide... 6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinoline- acetamide...

C - Chemistry, Metallurgy

07

D

260/284, 260/277

C07D 217/12 (2006.01)

Patent

CA 1100971

ABSTRACT OF THE DISCLOSURE The invention discloses novel 6,7-dimethoxy- and diethoxy-1,2,3,4- tetrahydro-1-isoquinoline derivatives of the general formulae (I) Image and Image (VIII) wherein R1 is hydrogen or benzyloxy-carbonyl, R2 is aryl, substituted aryl or heteroaryl, R4 is methyl or ethyl; and to a process for the preparation thereof. The invention is also directed to pharmaceutical compositions containing these compounds as active ingredi- ent. The compounds of the present invention are effective antiinflammatory agents.

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