6,8 dioxabicyclo¬3.2.1|octanes as inhibitors of leukotriene...

Details 6,8 dioxabicyclo¬3.2.1|octanes as inhibitors of leukotriene... 6,8 dioxabicyclo¬3.2.1|octanes as inhibitors of leukotriene...

C - Chemistry, Metallurgy

07

H

C07H 19/01 (2006.01) A61K 31/33 (2006.01) A61K 31/70 (2006.01) C07D 493/08 (2006.01) C07D 495/08 (2006.01) C07D 497/08 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2138631

Compounds having the formula I: (see fig.I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, antiallergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.

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