6,9-disubstituted purine derivatives and their use as...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/16 (2006.01) C07D 473/34 (2006.01)

Patent

CA 2710981

Certain 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are provided. These 6,9- disubstituted purine derivatives and their pharmaceutically acceptable salts are useful in compositions for treating mammalian cells, and especially human skin cells, in order to ameliorate the adverse effects of aging, treat skin disease states, treat immuno-logical responses resulting from or associated with inflammation, and the like.

La présente invention concerne des dérivés de purine 6,9-disubstituée et leurs sels pharmaceutiquement acceptables. Ces dérivés de purine 6,9-disubstituée et leurs sels pharmaceutiquement acceptables sont utiles dans des compositions destinées au traitement de cellules mammaliennes, et spécialement des cellules cutanées humaines, afin d'améliorer les effets indésirables du vieillissement, de traiter des états pathologiques cutanés, de traiter des réponses immunologiques résultant de ou associées à une inflammation, et analogues.

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