C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/104, 260/114
C07D 499/44 (2006.01) C07D 307/46 (2006.01) C07D 307/54 (2006.01) C07D 333/22 (2006.01) C07D 333/24 (2006.01) C07D 499/00 (2006.01) C07D 501/20 (2006.01)
Patent
CA 1056373
ABSTRACT OF THE DISCLOSURE Novel antibiotic compounds which are 7.beta.-acrylamidoceph- 3-em-4-carboxylic acids, and non-toxic derivatives thereof wherein the acrylamido group has the structure Image wherein A is aryl group and B is a substituted or unsubstituted lower alkyl, lower alkenyl or lower alkynyl group; or an aryl, cycloalkyl or cycloalkenyl group. These compounds possess antibacterial activity against gram-positive and gram-negative organisms coupled with stability to .beta.-lactamases. The invention further relates to the administration of the compounds.
215228
Gregory Gordon I.
Gregson Michael
Webb Godfrey B.
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