C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/227 (2006.01) A61K 31/4704 (2006.01) A61K 31/498 (2006.01) A61P 1/04 (2006.01) A61P 13/12 (2006.01) A61P 19/02 (2006.01) A61P 21/00 (2006.01) A61P 25/28 (2006.01) C07D 241/44 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 407/06 (2006.01) C07D 407/12 (2006.01)
Patent
CA 2546300
The present invention provides compounds of formula (I) and compounds of formula (I), (VII-a), as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitors wherein n, R1, R2, R3, R4, R5, R6, R7, Re, Rd and X have defined meanings.
L'invention concerne des composés de formule (I), des composés de formule (VII-a), des compostions pharmaceutiques renfermant ces composés et l'utilisation de ceux-ci comme inhibiteurs de la PARP, dans lesquelles: n, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?e¿, R?d¿ et X ont les significations présentées dans la description.
Guillemont Jerome Emile Georges
Mabire Dominique Jean-Pierre
Somers Maria Victorina Francisca
Van Dun Jacobus Alphonsus Josephus
Wouters Walter Boudewijn Leopold
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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