6 .alpha.-methylhydrocortisone derivatives and their...

C - Chemistry – Metallurgy – 07 – J

Patent

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195/19, 260/76

C07J 5/00 (2006.01) C07J 21/00 (2006.01) C12P 33/08 (2006.01) C12P 33/16 (2006.01)

Patent

CA 1185234

ABSTRACT Novel 6a-methlhydrocortisone derivatives of the general formula I Image (I) (in which R1 represents C2-C6-1-oxoalkyl or benzeyl and R2 represents H or C2-C6-1-oxoalkyl) and processes for their manufacture. The novel compounds of the formula I have an anti- inflammatory activity and accordingly may be used as anti-inflammatory agents and may be made up with suitable carriers into pharmaceutical preparations.

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