6-amino-1h-indazole and 4-aminobenzofuran compounds as...

Details 6-amino-1h-indazole and 4-aminobenzofuran compounds as... 6-amino-1h-indazole and 4-aminobenzofuran compounds as...

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/343 (2006.01) A61K 31/416 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 407/04 (2006.01)

Patent

CA 2492911

PDE4 inhibition is achieved by novel compounds, e.g., aminoindazole and aminobenzofuran analogs. The compounds of the present invention are of Formulas I and II: wherein R1, R2, R3, R4, R7 and R8 are as defined herein.

Selon l'invention, l'inhibition de phosphodiestérase 4 est effectuée par des nouveaux composés, par exemple des analogues d'aminoindazole et d'aminobenzofurane. L'invention concerne les composés de formule (I) et de formule (II), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?7¿ et R?8¿ sont définis dans la description.

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