C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/111
C07D 499/00 (2006.01)
Patent
CA 1080697
ABSTRACT OF THE DISCLOSURE: 6'-Amino-spiro [ cycloalkane-1,2'-penam ]-3'-carboxylic acid derivatives having the formula Image wherein n i5 a whole number of from 3 to 6 and R1 represents a hydrogen atom and R2 is a radical selected from the group consisting of 2-phenylacetyl, 2,6-dimethoxybenzoyl, 2-amino-2- phenylacetyl, 5-methyl-3-phenyl-4-isoxazolecarbonyl and 2-carboxy-2-phenylacetyl radical and their pharmaceutically acceptable, non-toxic salts, have valuable antibacterial properties and are useful as therapeutic agents in the treatment of infections diseases caused by Gram-positive and Gram-negative bacteria. Processes for preparing these compounds are also described.
279014
Leclercq Jacques
Rodriguez Ludovic
Na
Ucb S.a.
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