6'-amino-spiro cycloalkane-1,2'-penam -3'-carboxylic acids

C - Chemistry – Metallurgy – 07 – D

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C07D 499/42 (2006.01) C07D 277/60 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1081691

A B S T R A C T o f t h e D I S C L O S U R E 6'-Amino-spiro[cycloalkane-1,2'-penam]-3'-carboxylic acids of the formula Image wherein Z is a hydrogen or an alkali metal atom, or a protective group, and n a whole number of from 3 to 6, and process of preparing the same. These compounds are useful as intermediates in the synthesis of a new group of antibiotics having properties similar to the penicillins.

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