6-aminoisoquinoline compounds

Details 6-aminoisoquinoline compounds 6-aminoisoquinoline compounds

C - Chemistry, Metallurgy

07

D

C07D 217/14 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2675128

6-Amino isoquinoline compounds are provided that influence, inhibit or reduce the action of a kinase. Pharmaceutical compositions including therapeutically effective amounts of the 6-aminoisoquinoline compounds and pharmaceutically acceptable carriers are also provided. Various methods using the compounds and/or compositions to affect disease states or conditions such as cancer, obesity and glaucoma are also provided.

L'invention concerne des composés 6-aminoisoquinoline permettant d'influencer, d'inhiber ou de réduire l'action d'une kinase. L'invention concerne également des compositions pharmaceutiques comprenant des doses thérapeutiquement efficaces de composés 6-aminoisoquinoline et des supports pharmaceutiquement acceptables. Elle se rapporte en outre à diverses méthodes faisant appel à ces composés et/ou compositions pour agir sur des pathologies ou des affections telles que le cancer, l'obésité et le glaucome.

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