6-(aminomethyl)penicillanic acid 1,1-dioxide esters and...

C - Chemistry – Metallurgy – 07 – D

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260/118.5

C07D 499/04 (2006.01) C07D 307/88 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1206957

6-(AMINOMETHYL)PENICILLANIC ACID l,l- DIOXIDE ESTERS AND INTERMEDIATES THEREFOR Abstract 6-alpha- and 6-beta-(Aminomethyl)penicillanic acid l,l-dioxide esters which are hydrolyzable under physiological conditions, particularly those wherein the ester radical is lH-isobenzofuran-3-on-l-yl or (5-methyl-l,3-dioxol-2-on-4-yl)methyl, and an improved process and intermediates used in their synthesis.

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