6-aminopenicillanic acid esters

Details 6-aminopenicillanic acid esters 6-aminopenicillanic acid esters

C - Chemistry, Metallurgy

07

D

260/118

C07D 499/42 (2006.01)

Patent

CA 1238311

7566-720D ABSTRACT OF THE DISCLOSURE Disclosed are intermediates of the general formula (V) Image wherein R1 represents a hydrogen atom, a methyl group or an aryl group, and R2 represents a hydrogen atom or may be taken together with R1 to form a divalent carbon chain residue, or its acid addition salt. The intermediates may be used for preparing novel Ampicillin esters by reacting with phenylglycine of the formula Ph-CH(NH2)-COOH. The intermediates are prepared by reacting a compound of the formula Image (III) wherein R1 and R2 are as defined above, and X is a halogen atom, with a (6-protected)-aminopenicillanic acid or its salt.

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