6-aryl/heteroalkyloxy benzothiazole and benzimidazole...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 235/30 (2006.01) A61K 31/4184 (2006.01) A61K 31/428 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) C07D 277/82 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2702791

The invention relates to novel products of the formula (I) in which : R is H, HaI or AIk; A is NH or S; R5 is H or Alk optionally substituted by one or more HaI; R6 is an optionally substituted aryl or heteroaryl; W is H or COR7 in which R7 is a cycloalkyl, an optionally substituted alkyl, an optionally substituted alkoxy or NR1 R2 with one of R1 and R2 being H or alk while the other of R1 and R2 is a cycloakyl or an optionally substituted alkyl; or R1 and R2 form together with N to which they are bonded; a cyclic radical optionally including one or more optionally substituted O, S, N and NH; the invention also relates to said products in any of their isomer forms or as salts, and they can be used as drugs, in particular as c-Met inhibitors.

L'invention concerne les nouveaux produits de formule (I); dans laquelle R représente H1 HaI ou AIk; A représente NH ou S; R5 représente H ou alk éventuellement substitué par un ou plusieurs HaI; R6 représente aryle ou hétéroaryle éventuellement substitués; W représente H ou COR7 dans lequel R7 représente cycloalkyle, alkyle éventuellement substitué, alcoxy éventuellement substitué ou NR1R2 avec l'un de R1 et R2 représente H ou alk et l'autre de R1 et R2 représente cycloalkyle ou aikyle éventuellement substitué; ou bien R1 et R2 forment avec N auquel ils sont liés un radical cyclique renfermant éventuellement un ou plusieurs O, S, N et NH, éventuellement substitué; ces produits étant sous toutes les formes isomères et les sels, à titre de médicaments notamment comme inhibiteurs de CMet for the treatment of cancer.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

6-aryl/heteroalkyloxy benzothiazole and benzimidazole... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 6-aryl/heteroalkyloxy benzothiazole and benzimidazole..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6-aryl/heteroalkyloxy benzothiazole and benzimidazole... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1725059

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.